PDXDC1

Across TCGA cell cohorts, PDXDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,543 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PDXDC1-associated genes across cancer lineages are SRRM1, ZBTB46, and ALG3. Each is linked with PDXDC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PDXDC1-to-partner and partner-to-PDXDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDXDC1 versus SRRM1 in STOMACH, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDXDC1→partner) and Y-score (partner→PDXDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SRRM1 →	+0.689	+1.194	<.001	.003	3	4
BLOOD_Leukemia	ZBTB46 →	+0.941	+0.804	.005	.007	3	4
OESOPHAGUS	ALG3 →	-1.112	-0.604	.002	.003	3	4
LIVER	ORMDL3 →	+1.324	+0.827	.001	.003	3	4
BREAST	POU2F1 →	+0.594	+0.785	.001	.006	3	4
BREAST	PBRM1 →	+1.078	+1.082	.002	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,543 associations by consensus.

PDXDC1 vs SRRM1 — STOMACH

Explore this scatter interactively →