PDSS1P1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PDSS1P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,271 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDSS1P1-associated proteins across cancer lineages are PSMB6, SAMHD1, and PSMB10. Each is linked with PDSS1P1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PDSS1P1-to-partner and partner-to-PDSS1P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDSS1P1 versus PSMB6 in HNSC, with a Pearson correlation of -0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDSS1P1→partner) and Y-score (partner→PDSS1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCPSMB6 →-0.474-0.911<.001<.00137
HNSCSAMHD1 →+0.595+0.581<.001<.00137
HNSCPSMB10 →+0.567+0.800<.001<.00136
HNSCBTK →+0.530+0.715<.001<.00136
GBMGIMAP4 →+0.634+0.594<.001<.00136
HNSCGIMAP7 →+0.663+0.722<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,271 associations by consensus.

PDSS1P1 vs PSMB6 — HNSC

Per-sample scatter of PDSS1P1 vs PSMB6 in HNSC (Pearson r = -0.54).

Explore this scatter interactively →

Exploration