PDSS1

Across TCGA patient cohorts, PDSS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,444 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDSS1-associated proteins across cancer lineages are FEN1, MCM3, and MCM5. Each is linked with PDSS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PDSS1-to-partner and partner-to-PDSS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDSS1 versus FEN1 in OV, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDSS1→partner) and Y-score (partner→PDSS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FEN1 →	+0.466	+0.432	.003	.005	3	8
LUAD	MCM3 →	+0.686	+0.542	<.001	<.001	3	8
LUAD	MCM5 →	+0.682	+0.529	<.001	<.001	3	8
LUAD	MCM6 →	+0.686	+0.529	<.001	<.001	3	8
LSCC	RNF20 →	+0.264	+0.574	<.001	<.001	3	8
LUAD	NCAPD2 →	+0.679	+0.532	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,444 associations by consensus.

PDSS1 vs FEN1 — OV

Explore this scatter interactively →