PDSS1

Across TCGA patient cohorts, PDSS1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,212 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PDSS1-associated genes across cancer lineages are NCAPG, DLGAP5, and CCNB1. Each is linked with PDSS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PDSS1-to-partner and partner-to-PDSS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDSS1 versus NCAPG in LUAD, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDSS1→partner) and Y-score (partner→PDSS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NCAPG →	+1.285	+0.572	.001	.001	3	3
LUAD	DLGAP5 →	+1.753	+0.686	<.001	<.001	3	3
LUAD	CCNB1 →	+1.373	+0.637	.001	.002	3	3
LUAD	CX3CR1 →	-1.422	-0.783	<.001	<.001	3	3
LUAD	DEPDC1B →	+1.315	+0.859	.001	<.001	3	3
BRCA	RPL7P39 →	-0.305	-0.379	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,212 associations by consensus.

PDSS1 vs NCAPG — LUAD

Explore this scatter interactively →