PDPR

Across TCGA pan-cancer cohorts, PDPR RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated PDPR data layer compared with 4 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PDPR RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PDPR expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

ACC, BLCA, and HNSC are the cancer types where PDPR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.180	0.666	<.001	100	view →
BLCA	DFS	Median	All	0.232	0.423	<.001	57	view →
HNSC	DFS	Median	All	0.778	0.640	<.001	50	view →
UCS	DFS	Tertile	IV	0.936	0.323	.024	24	view →
KIRC	OS	Tertile	All	0.732	0.528	.003	19	view →
LIHC	DFS	Quartile	All	0.459	0.631	.001	16	view →
CHOL	OS	Median	All	0.846	0.308	.014	15	view →
THYM	DFS	Median	III,IV	1.000	0.402	.004	14	view →
LUSC	DFS	Quartile	III,IV	0.227	0.903	.001	10	view →
UVM	DFS	Quartile	All	0.727	0.345	.041	9	view →
SCLC	OS	Median	III,IV	0.573	0.272	.006	9	view →
THCA	DFS	Quartile	All	0.926	0.964	.015	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

PDPR–ACC (DFS)

Open the ACC breakdown →