PDPN

Across TCGA pan-cancer cohorts, PDPN Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PDPN data layer compared with 28 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PDPN Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated PDPN expression acts as an unfavorable survival marker, although some lineages such as UCEC and OV show a favorable association.

UCEC and OV are the cancer types where PDPN Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.621	.011	28	view →
OV	DFS	Median	All	1.000	0.154	.024	8	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PDPN–UCEC (DFS)

Open the UCEC breakdown →