PDPK1

Across TCGA cell cohorts, PDPK1 RNA expression is significantly associated with the RNA expression of many other genes, with 11,224 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PDPK1-associated genes across cancer lineages are SMG1, USP7, and RNPS1. Each is linked with PDPK1 in more than 18 cancer types. Because this analysis shows association rather than direction, both PDPK1-to-partner and partner-to-PDPK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDPK1 versus SMG1 in PANCREAS, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDPK1→partner) and Y-score (partner→PDPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	SMG1 →	+1.073	+0.901	<.001	<.001	3	19
STOMACH	USP7 →	+1.152	+1.249	<.001	<.001	3	19
BLOOD_Myeloma	RNPS1 →	+1.063	+1.223	<.001	<.001	3	19
STOMACH	CREBBP →	+1.617	+1.271	<.001	<.001	3	19
BLOOD_Myeloma	KCTD5 →	+1.215	+1.065	.001	<.001	2	19
BLOOD_Lymphoma	MRTFB →	+1.269	+1.220	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,224 associations by consensus.

PDPK1 vs SMG1 — PANCREAS

Explore this scatter interactively →