PDP2

Across TCGA cell cohorts, PDP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,547 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PDP2-associated GO terms across cancer lineages are Heterochromatin formation, Copper ion export, and Nucleic acid catabolic process. Each is linked with PDP2 in more than 12 cancer types. Because this analysis shows association rather than direction, both PDP2-to-partner and partner-to-PDP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by PDP2-low versus PDP2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDP2→partner) and Y-score (partner→PDP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Heterochromatin formation →	+0.068	+0.986	.001	.001	3	13
LUNG_NSCLC_LUSC	Copper ion export →	-0.181	-1.025	<.001	<.001	3	13
BONE	Nucleic acid catabolic process →	+0.062	+1.030	<.001	<.001	3	12
BONE	RNA catabolic process →	+0.075	+1.216	<.001	<.001	3	12
BLOOD_Lymphoma	Regulation of mRNA catabolic process →	+0.065	+0.966	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of autophagosome maturation →	+0.081	+0.780	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,547 associations by consensus.

Heterochromatin formation by PDP2 expression — STOMACH

Explore this box plot interactively →