PDP2

Across TCGA cell cohorts, PDP2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDP2-associated genes across cancer lineages are MYOD1, SPRR1A, and CNGA2. Each is linked with PDP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDP2-to-partner and partner-to-PDP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOD1 grouped by PDP2-low versus PDP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDP2→partner) and Y-score (partner→PDP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYOD1 →	+0.022	+4.922	<.001	.009	3	1
BLOOD_Leukemia	SPRR1A →	+0.194	+5.201	<.001	.006	3	1
BLOOD_Leukemia	CNGA2 →	+0.099	+5.539	<.001	.003	3	1
BLOOD_Leukemia	GALP →	+0.031	+5.201	.001	.006	3	1
LARGE_INTESTINE	OR2M5 →	+0.016	+4.415	<.001	.007	3	1
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MYOD1 by PDP2 expression — BLOOD_Leukemia

Explore this box plot interactively →