PDLIM3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PDLIM3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,163 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PDLIM3-associated genes across cancer lineages are TPM1, PDLIM7, and TPM2. Each is linked with PDLIM3 in more than 9 cancer types. Because this analysis shows association rather than direction, both PDLIM3-to-partner and partner-to-PDLIM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDLIM3 versus TPM1 in OV, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDLIM3→partner) and Y-score (partner→PDLIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTPM1 →+1.096+0.896<.001<.001310
OVPDLIM7 →+1.137+0.924<.001<.001310
OVTPM2 →+1.483+0.989<.001<.001310
COADMYL9 →+1.350+0.620<.001<.00139
OVMEDAG →+2.011+1.037<.001<.00139
OVAEBP1 →+2.615+1.130<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,163 associations by consensus.

PDLIM3 vs TPM1 — OV

Per-sample scatter of PDLIM3 vs TPM1 in OV (Pearson r = 0.63).

Explore this scatter interactively →

Exploration