PDLIM1P3

Across TCGA patient cohorts, PDLIM1P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,038 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PDLIM1P3-associated GO terms across cancer lineages are Regulation of protein serine/threonine kinase activity, Regulation of chromosome organization, and Negative regulation of DNA metabolic process. Each is linked with PDLIM1P3 in more than 10 cancer types. Because this analysis shows association rather than direction, both PDLIM1P3-to-partner and partner-to-PDLIM1P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein serine/threonine kinase activity grouped by PDLIM1P3-low versus PDLIM1P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDLIM1P3→partner) and Y-score (partner→PDLIM1P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein serine/threonine kinase activity →	+0.081	+0.091	<.001	<.001	3	11
STAD	Regulation of chromosome organization →	+0.108	+0.084	<.001	<.001	3	11
STAD	Negative regulation of DNA metabolic process →	+0.083	+0.064	<.001	<.001	3	11
STAD	Positive regulation of binding →	+0.091	+0.080	<.001	<.001	3	11
STAD	Protein-DNA complex assembly →	+0.094	+0.091	<.001	<.001	3	11
STAD	Mitotic spindle organization →	+0.112	+0.084	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,038 associations by consensus.

Regulation of protein serine/threonine kinase activity by PDLIM1P3 expression — STAD

Explore this box plot interactively →