PDLIM1

Across TCGA patient cohorts, PDLIM1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,753 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDLIM1-associated genes across cancer lineages are USP14, NCAPH, and LRFN1. Each is linked with PDLIM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PDLIM1-to-partner and partner-to-PDLIM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDLIM1 versus USP14 in HNSC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDLIM1→partner) and Y-score (partner→PDLIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	USP14 →	-0.624	-0.310	.004	.001	3	5
BRCA	NCAPH →	-0.781	-0.409	.001	.003	3	5
BRCA	LRFN1 →	-0.592	-0.336	<.001	<.001	3	5
UCEC	SCLY →	-0.493	-0.383	<.001	.002	3	5
LSCC	FAM186B →	-0.451	-0.444	<.001	<.001	3	5
COAD	POU2F1 →	-0.632	-0.261	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,753 associations by consensus.

PDLIM1 vs USP14 — HNSC

Explore this scatter interactively →