PDIA5

Across TCGA patient cohorts, PDIA5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,346 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDIA5-associated proteins across cancer lineages are P4HA2, FKBP10, and PLOD1. Each is linked with PDIA5 in more than 4 cancer types. Because this analysis shows association rather than direction, both PDIA5-to-partner and partner-to-PDIA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDIA5 versus P4HA2 in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDIA5→partner) and Y-score (partner→PDIA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	P4HA2 →	+0.831	+0.551	<.001	<.001	3	5
GBM	FKBP10 →	+0.456	+0.448	<.001	.006	3	5
GBM	PLOD1 →	+0.595	+0.552	<.001	<.001	3	4
GBM	CLASP2 →	-0.320	-0.457	<.001	<.001	3	4
GBM	DNAJC13 →	+0.291	+0.537	<.001	<.001	3	4
BRCA	FNDC3B →	+0.378	+0.621	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,346 associations by consensus.

PDIA5 vs P4HA2 — GBM

Explore this scatter interactively →