PDIA5

Across TCGA cell cohorts, PDIA5 RNA expression is significantly associated with the RNA expression of many other genes, with 10,153 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDIA5-associated genes across cancer lineages are RPN1, TMEM39A, and SSR1. Each is linked with PDIA5 in more than 15 cancer types. Because this analysis shows association rather than direction, both PDIA5-to-partner and partner-to-PDIA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDIA5 versus RPN1 in STOMACH, with a Pearson correlation of 0.68.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDIA5→partner) and Y-score (partner→PDIA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	RPN1 →	+1.110	+1.355	<.001	<.001	3	16
OESOPHAGUS	TMEM39A →	+1.212	+1.321	.002	<.001	2	14
UPPER_AERODIGESTIVE_TRACT	SSR1 →	+1.127	+1.033	<.001	<.001	3	12
BLOOD_Myeloma	PDIA6 →	+1.336	+1.444	<.001	<.001	3	12
BREAST	SEC61A1 →	+0.968	+1.132	.001	.001	1	14
KIDNEY	MOGS →	+0.874	+1.593	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,153 associations by consensus.

PDIA5 vs RPN1 — STOMACH

Explore this scatter interactively →