PDIA2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PDIA2 mutation is significantly associated with the RNA expression of many other genes, with 963 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDIA2-associated genes across cancer lineages are RN7SL415P, RN7SKP92, and MIR8075. Each is linked with PDIA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDIA2-to-partner and partner-to-PDIA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDIA2→partner) and Y-score (partner→PDIA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL415P →+0.105+4.812<.001.00632
CESCRN7SKP92 →+0.169+4.812<.001.00632
SKCMMIR8075 →+0.191+4.900<.001.00232
SKCMPPIAL4F →+0.110+3.596<.001.00132
COADRNA5SP305 →+0.482+3.130.001.00332
COADRNU6-694P →+0.316+4.571<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 963 associations by consensus.

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