PDGFRB

Across TCGA cell cohorts, PDGFRB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,137 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PDGFRB-associated GO terms across cancer lineages are Metanephric glomerulus morphogenesis, Metanephric glomerulus vasculature morphogenesis, and Metanephric glomerular capillary formation. Each is linked with PDGFRB in more than 17 cancer types. Because this analysis shows association rather than direction, both PDGFRB-to-partner and partner-to-PDGFRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metanephric glomerulus morphogenesis grouped by PDGFRB-low versus PDGFRB-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDGFRB→partner) and Y-score (partner→PDGFRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Metanephric glomerulus morphogenesis →	+1.462	+2.453	<.001	<.001	3	18
BONE	Metanephric glomerulus vasculature morphogenesis →	+1.462	+2.453	<.001	<.001	3	18
BONE	Metanephric glomerular capillary formation →	+1.462	+2.453	<.001	<.001	3	18
LIVER	Cell migration involved in vasculogenesis →	-0.307	-1.948	<.001	<.001	3	16
URINARY_TRACT	Aorta smooth muscle tissue morphogenesis →	+1.152	+0.866	<.001	.007	3	13
OVARY	VEGF-activated platelet-derived growth factor receptor signaling pathway →	-0.388	-1.462	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,137 associations by consensus.

Metanephric glomerulus morphogenesis by PDGFRB expression — BONE

Explore this box plot interactively →