PDGFD

Across TCGA pan-cancer cohorts, PDGFD mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PDGFD data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher PDGFD mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PDGFD expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

PDAC, LUAD, and CCRCC are the cancer types where PDGFD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.292	0.464	.010	13	view →
LUAD	DFS	Tertile	II,III,IV	0.325	0.785	.013	11	view →
CCRCC	OS	Median	III,IV	0.924	0.615	.021	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PDGFD–PDAC (DFS)

Open the PDAC breakdown →