PDGFD

Across TCGA patient cohorts, PDGFD RNA expression is significantly associated with the protein abundance of many other proteins, with 19,713 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PDGFD-associated proteins across cancer lineages are TNS2_S120, PRKG1, and ARHGEF17. Each is linked with PDGFD in more than 7 cancer types. Because this analysis shows association rather than direction, both PDGFD-to-partner and partner-to-PDGFD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDGFD versus TNS2_S120 in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDGFD→partner) and Y-score (partner→PDGFD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TNS2_S120 →	+0.667	+0.936	<.001	<.001	3	8
CCRCC	PRKG1 →	+0.692	+1.520	<.001	<.001	3	8
CCRCC	ARHGEF17 →	+0.519	+1.449	<.001	<.001	3	8
UCEC	CALD1 →	+0.785	+0.685	<.001	.004	3	8
UCEC	SORBS3 →	+0.494	+0.776	.004	.008	2	8
LSCC	TLN2 →	+0.641	+1.033	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,713 associations by consensus.

PDGFD vs TNS2_S120 — LSCC

Explore this scatter interactively →