PDGFD

Across TCGA cell cohorts, PDGFD RNA expression is significantly associated with the go_rna of many other GO terms, with 2,836 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDGFD-associated GO terms across cancer lineages are Positive regulation of monocyte extravasation, Regulation of smooth muscle cell chemotaxis, and Primary heart field specification. Each is linked with PDGFD in more than 10 cancer types. Because this analysis shows association rather than direction, both PDGFD-to-partner and partner-to-PDGFD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of monocyte extravasation grouped by PDGFD-low versus PDGFD-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDGFD→partner) and Y-score (partner→PDGFD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of monocyte extravasation →	-0.338	-1.226	.009	<.001	3	11
STOMACH	Regulation of smooth muscle cell chemotaxis →	-0.246	-1.314	<.001	<.001	3	8
STOMACH	Primary heart field specification →	+1.051	+1.593	<.001	<.001	3	7
PANCREAS	Regulation of monocyte extravasation →	-0.306	-1.296	<.001	<.001	3	7
STOMACH	Negative regulation of protein catabolic process →	+0.107	+1.654	<.001	.003	3	6
LUNG_NSCLC_LUSC	Cytoplasmic translational initiation →	+0.092	+1.355	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,836 associations by consensus.

Positive regulation of monocyte extravasation by PDGFD expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →