Across TCGA patient cohorts, PDGFA protein abundance is significantly associated with the RNA expression of many other genes, with 4,490 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDGFA-associated genes across cancer lineages are STK32B, RNF19A, and MTCL1. Each is linked with PDGFA in more than 2 cancer types. Because this analysis shows association rather than direction, both PDGFA-to-partner and partner-to-PDGFA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDGFA→partner) and Y-score (partner→PDGFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STK32B →	+1.381	+0.986	.006	.004	3	3
HNSC	RNF19A →	-0.786	-0.966	.005	.006	3	3
CCRCC	MTCL1 →	+1.145	+2.287	.003	.003	3	3
GBM	NTM →	+1.037	+0.866	.009	.004	3	3
UCEC	PLBD1 →	-1.638	-1.440	.002	.003	2	3
UCEC	ABHD12B →	+2.559	+1.328	.009	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,490 associations by consensus.

Exploration

PDGFA survival (RNA) · tumor vs normal (RNA) · all PDGFA data types