PDGFA

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PDGFA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,767 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PDGFA-associated GO terms across cancer lineages are Regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway, Regulation of metanephric mesenchymal cell migration, and Positive regulation of metanephric mesenchymal cell migration. Each is linked with PDGFA in more than 17 cancer types. Because this analysis shows association rather than direction, both PDGFA-to-partner and partner-to-PDGFA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDGFA→partner) and Y-score (partner→PDGFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINRegulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway →+1.480+3.098<.001<.001318
SKINRegulation of metanephric mesenchymal cell migration →+1.577+3.233<.001<.001318
SKINPositive regulation of metanephric mesenchymal cell migration →+1.480+3.098<.001<.001318
SKINPositive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway →+1.480+3.098<.001<.001318
CNSRegulation of phosphatidylinositol biosynthetic process →+1.567+2.206<.001<.001317
LUNG_NSCLC_LUSCPeptidyl-tyrosine autophosphorylation →+0.232+1.617<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,767 associations by consensus.

Exploration