Across TCGA patient cohorts, PDE9A-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,033 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDE9A-AS1-associated proteins across cancer lineages are NADK, USP15_S229, and MYEF2. Each is linked with PDE9A-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PDE9A-AS1-to-partner and partner-to-PDE9A-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE9A-AS1→partner) and Y-score (partner→PDE9A-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NADK →	-0.408	-0.498	<.001	<.001	3	7
BRCA	USP15_S229 →	-0.616	-0.175	<.001	.001	3	5
LSCC	MYEF2 →	+0.748	+0.392	.002	.005	3	5
GBM	RPL5 →	-0.287	-0.681	<.001	<.001	3	4
GBM	RPL7 →	-0.366	-0.648	<.001	<.001	3	4
HNSC	ZMYM3 →	+0.235	+0.393	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,033 associations by consensus.

Exploration

PDE9A-AS1 survival (RNA) · tumor vs normal (RNA) · all PDE9A-AS1 data types