PDE8B

Across TCGA patient cohorts, PDE8B RNA expression is significantly associated with the RNA expression of many other genes, with 19,659 significant associations in total. UVM shows the largest number of these associations.

The most reproducible PDE8B-associated genes across cancer lineages are POLK, AGGF1, and BPTF. Each is linked with PDE8B in more than 31 cancer types. Because this analysis shows association rather than direction, both PDE8B-to-partner and partner-to-PDE8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE8B versus POLK in UVM, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE8B→partner) and Y-score (partner→PDE8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	POLK →	+1.366	+0.674	<.001	<.001	3	32
UVM	AGGF1 →	+1.379	+0.653	<.001	<.001	3	32
UVM	BPTF →	+1.182	+0.647	<.001	<.001	3	32
THCA	ZBED3-AS1 →	+0.566	+1.556	<.001	<.001	3	32
UVM	FAM20B →	+1.240	+0.654	<.001	<.001	3	31
UVM	RAD17 →	+1.203	+0.586	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,659 associations by consensus.

PDE8B vs POLK — UVM

Explore this scatter interactively →