PDE8B

Across TCGA patient cohorts, PDE8B RNA expression is significantly associated with the protein abundance of many other proteins, with 12,466 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PDE8B-associated proteins across cancer lineages are TBX2_S360, UTRN, and NID1. Each is linked with PDE8B in more than 4 cancer types. Because this analysis shows association rather than direction, both PDE8B-to-partner and partner-to-PDE8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE8B versus TBX2_S360 in PDAC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE8B→partner) and Y-score (partner→PDE8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TBX2_S360 →	+0.610	+0.333	<.001	<.001	3	5
UCEC	UTRN →	+0.293	+0.857	<.001	<.001	3	4
UCEC	NID1 →	+0.476	+0.789	.001	<.001	3	4
HNSC	NRDC →	-0.264	-0.454	<.001	.001	3	4
BRCA	OLFML3 →	+0.793	+0.652	<.001	<.001	3	4
LSCC	MYEF2_S17 →	+0.732	+0.234	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,466 associations by consensus.

PDE8B vs TBX2_S360 — PDAC

Explore this scatter interactively →