Across TCGA patient cohorts, PDE7A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,842 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PDE7A-associated proteins across cancer lineages are EML2, PDE7A_S84, and FAM83E_S351. Each is linked with PDE7A in more than 4 cancer types. Because this analysis shows association rather than direction, both PDE7A-to-partner and partner-to-PDE7A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE7A→partner) and Y-score (partner→PDE7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EML2 →	-0.702	-1.034	<.001	<.001	3	5
LSCC	PDE7A_S84 →	+0.713	+0.685	<.001	<.001	3	5
BRCA	FAM83E_S351 →	-0.846	-0.582	.002	.002	3	4
LSCC	GIPC1 →	-0.426	-0.815	<.001	<.001	3	4
OV	MYO9B →	+0.328	+0.820	.005	.002	3	4
BRCA	NAPG →	-0.323	-0.655	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,842 associations by consensus.

Exploration

PDE7A survival (RNA) · tumor vs normal (RNA) · all PDE7A data types