Across TCGA cell cohorts, PDE7A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,904 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PDE7A-associated GO terms across cancer lineages are Regulation of double-strand break repair, Positive regulation of double-strand break repair, and Regulation of centrosome cycle. Each is linked with PDE7A in more than 14 cancer types. Because this analysis shows association rather than direction, both PDE7A-to-partner and partner-to-PDE7A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE7A→partner) and Y-score (partner→PDE7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of double-strand break repair →	+0.077	+0.934	<.001	.006	3	15
BONE	Positive regulation of double-strand break repair →	+0.082	+0.973	<.001	.002	3	15
LUNG_SCLC	Regulation of centrosome cycle →	+0.091	+0.823	.001	.005	3	15
SOFT_TISSUE	DNA recombination →	+0.060	+0.631	<.001	<.001	3	15
BONE	Epigenetic regulation of gene expression →	+0.073	+1.006	.001	.003	3	14
BONE	Positive regulation of DNA metabolic process →	+0.090	+1.221	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,904 associations by consensus.

Exploration

PDE7A survival (RNA) · tumor vs normal (RNA) · all PDE7A data types