Across TCGA pan-cancer cohorts, PDE4DIPP8 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated PDE4DIPP8 data layer.
The strongest signal is observed in kidney chromophobe (KICH), where higher PDE4DIPP8 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PDE4DIPP8 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LAML show a favorable association.
KICH, ACC, and READ are the cancer types where PDE4DIPP8 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.