PDE4DIPP7

Across TCGA pan-cancer cohorts, PDE4DIPP7 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PDE4DIPP7 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher PDE4DIPP7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PDE4DIPP7 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

MESO, HNSC, and PRAD are the cancer types where PDE4DIPP7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	II,III,IV	0.255	0.484	.002	45	view →
HNSC	DFS	Tertile	III,IV	0.704	0.540	.005	35	view →
PRAD	OS	Tertile	All	0.648	0.970	<.001	32	view →
READ	OS	Tertile	All	0.446	0.688	.008	26	view →
SKCM	OS	Tertile	II,III,IV	0.597	0.302	<.001	23	view →
ACC	OS	Tertile	IV	0.344	0.724	.038	21	view →
LGG	DFS	Tertile	All	0.312	0.466	.001	20	view →
STAD	DFS	Quartile	All	0.521	0.780	.010	16	view →
LUSC	DFS	Median	II,III,IV	0.284	0.475	.004	15	view →
THYM	OS	Quartile	II,III,IV	0.654	1.000	.004	13	view →
BRCA	DFS	Quartile	All	0.876	0.931	.010	12	view →
CHOL	DFS	Quartile	II,III,IV	0.105	0.464	.021	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PDE4DIPP7–MESO (DFS)

Open the MESO breakdown →