PDE4DIPP5

Across TCGA pan-cancer cohorts, PDE4DIPP5 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of PDE4DIPP5’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where PDE4DIPP5 RNA is repressed in tumor relative to normal tissue. In most cancer types PDE4DIPP5 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

BRCA, KICH, and COAD are the cancer types where PDE4DIPP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PDE4DIPP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.048	<.001	6	view →
KICH	All	All	−0.065	.001	5	view →
COAD	All	II,III,IV	−0.017	.012	4	view →
LUAD	Male	All	−0.039	.022	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

PDE4DIPP5–BRCA

Open the BRCA breakdown →