PDE4DIPP3

Across TCGA pan-cancer cohorts, PDE4DIPP3 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PDE4DIPP3’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where PDE4DIPP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PDE4DIPP3 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

BRCA, LUSC, and KIRP are the cancer types where PDE4DIPP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PDE4DIPP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.022	<.001	6	view →
LUSC	All	All	−0.048	<.001	4	view →
KIRP	All	All	+0.025	.029	2	view →
LUAD	Female	All	−0.036	.035	1	view →
KIRC	Male	All	+0.020	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

PDE4DIPP3–BRCA

Open the BRCA breakdown →