Across TCGA pan-cancer cohorts, PDE4DIPP10 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PDE4DIPP10’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PDE4DIPP10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PDE4DIPP10 is over-expressed in tumor.
HNSC and LUSC are the cancer types where PDE4DIPP10 tumor–normal differential expression is most reproducible.