Across TCGA patient cohorts, PDE4B-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,712 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDE4B-AS1-associated proteins across cancer lineages are PIK3AP1_S642, ARHGEF2, and PREX1. Each is linked with PDE4B-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PDE4B-AS1-to-partner and partner-to-PDE4B-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE4B-AS1→partner) and Y-score (partner→PDE4B-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIK3AP1_S642 →	+1.472	+2.159	<.001	.002	3	5
GBM	ARHGEF2 →	+0.243	+0.615	<.001	<.001	3	4
GBM	PREX1 →	+0.414	+0.575	<.001	.009	3	4
UCEC	PROX1_S179 →	+0.762	+1.297	<.001	<.001	3	4
HNSC	PSMB6 →	-0.430	-1.111	<.001	<.001	3	4
LSCC	SH3KBP1 →	+0.511	+0.784	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,712 associations by consensus.

Exploration

PDE4B-AS1 survival (RNA) · tumor vs normal (RNA) · all PDE4B-AS1 data types