PDE3B

Across TCGA patient cohorts, PDE3B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,336 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PDE3B-associated proteins across cancer lineages are ELMO1, ANKRD44, and SEPTIN1. Each is linked with PDE3B in more than 6 cancer types. Because this analysis shows association rather than direction, both PDE3B-to-partner and partner-to-PDE3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE3B versus ELMO1 in UCEC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE3B→partner) and Y-score (partner→PDE3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ELMO1 →	+0.476	+0.669	<.001	.005	3	7
UCEC	ANKRD44 →	+0.378	+0.568	<.001	<.001	3	7
UCEC	SEPTIN1 →	+0.721	+0.910	<.001	<.001	3	7
HNSC	CARMIL2_S1381 →	+0.979	+0.960	<.001	<.001	3	6
HNSC	DOCK10 →	+0.392	+0.701	.003	.004	3	6
UCEC	DOCK8 →	+0.439	+0.635	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,336 associations by consensus.

PDE3B vs ELMO1 — UCEC

Explore this scatter interactively →