PDE11A-AS1

Across TCGA pan-cancer cohorts, PDE11A-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated PDE11A-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PDE11A-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PDE11A-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and THYM show a favorable association.

ACC, STAD, and UCEC are the cancer types where PDE11A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	II,III,IV	0.175	0.581	<.001	127	view →
STAD	DFS	Median	All	0.611	0.802	.005	51	view →
UCEC	DFS	Quartile	All	0.838	0.915	.003	36	view →
THCA	OS	Tertile	II,III,IV	0.776	0.947	.008	27	view →
BLCA	DFS	Tertile	IV	0.147	0.482	.011	18	view →
SKCM	OS	Tertile	III,IV	0.528	0.742	.005	18	view →
KIRP	OS	Tertile	IV	0.035	0.405	.006	18	view →
LUAD	DFS	Tertile	IV	0.388	0.736	.024	18	view →
PCPG	OS	Tertile	All	0.794	0.981	.018	18	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	9	view →
COAD	OS	Median	IV	0.251	0.634	.032	9	view →
TGCT	DFS	Tertile	All	0.533	0.726	.023	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

PDE11A-AS1–ACC (DFS)

Open the ACC breakdown →