Across TCGA pan-cancer cohorts, PDCL3P3 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PDCL3P3’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where PDCL3P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PDCL3P3 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

BLCA, LUSC, and COAD are the cancer types where PDCL3P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PDCL3P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.275	.015	6	view →
LUSC	All	All	+0.129	<.001	5	view →
COAD	All	III,IV	+0.145	.035	3	view →
KIRC	All	III,IV	+0.030	.011	3	view →
KICH	Male	All	−0.084	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: PDCL3P3 RNA expression & survival · all PDCL3P3 data types