PDCL3

Across TCGA patient cohorts, PDCL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,410 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDCL3-associated proteins across cancer lineages are MKI67, BIRC6, and ADD1. Each is linked with PDCL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both PDCL3-to-partner and partner-to-PDCL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDCL3 versus MKI67 in LSCC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCL3→partner) and Y-score (partner→PDCL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MKI67 →	+0.569	+0.577	<.001	<.001	3	5
LSCC	BIRC6 →	+0.186	+0.672	<.001	<.001	3	5
GBM	ADD1 →	-0.372	-0.383	<.001	<.001	3	5
LSCC	EIF5B →	+0.232	+0.540	<.001	<.001	3	5
LSCC	NCAPH →	+0.711	+0.838	<.001	<.001	3	5
LSCC	PSME4 →	+0.363	+0.462	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,410 associations by consensus.

PDCL3 vs MKI67 — LSCC

Explore this scatter interactively →