PDCD5

Across TCGA patient cohorts, PDCD5 mutation is significantly associated with the RNA expression of many other genes, with 180 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDCD5-associated genes across cancer lineages are RNU6-271P, RNU1-57P, and RNU6-294P. Each is linked with PDCD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDCD5-to-partner and partner-to-PDCD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-271P grouped by PDCD5-low versus PDCD5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD5→partner) and Y-score (partner→PDCD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-271P →	+0.274	+3.630	<.001	.003	3	2
STAD	RNU1-57P →	+0.600	+5.026	<.001	.009	3	2
BLCA	RNU6-294P →	+0.278	+7.640	<.001	.009	3	1
BLCA	RNU6-1080P →	+0.268	+7.640	<.001	.009	3	1
UCEC	RPL23AP86 →	+0.241	+4.031	.001	<.001	3	1
UCEC	RN7SL470P →	+0.225	+2.694	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 180 associations by consensus.

RNU6-271P by PDCD5 expression — UCEC

Explore this box plot interactively →