PDCD5

Across TCGA cell cohorts, PDCD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,149 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDCD5-associated GO terms across cancer lineages are DNA replication initiation, snoRNA guided rRNA pseudouridine synthesis, and Maturation of SSU-rRNA. Each is linked with PDCD5 in more than 12 cancer types. Because this analysis shows association rather than direction, both PDCD5-to-partner and partner-to-PDCD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by PDCD5-low versus PDCD5-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD5→partner) and Y-score (partner→PDCD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication initiation →	+0.165	+0.621	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	snoRNA guided rRNA pseudouridine synthesis →	+0.096	+0.902	<.001	<.001	3	12
BLOOD_Lymphoma	Maturation of SSU-rRNA →	+0.118	+0.523	<.001	.003	3	11
LUNG_SCLC	Ribosomal small subunit biogenesis →	+0.097	+0.670	<.001	.001	3	11
BREAST	Nucleolar large rRNA transcription by RNA polymerase I →	+0.110	+0.854	<.001	.001	2	12
UPPER_AERODIGESTIVE_TRACT	Lipid translocation →	-0.068	-0.726	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,149 associations by consensus.

DNA replication initiation by PDCD5 expression — BLOOD_Myeloma

Explore this box plot interactively →