PDCD4

Across TCGA patient cohorts, PDCD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,608 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PDCD4-associated proteins across cancer lineages are PDCD4_S457, PDCD4_S76, and RPS6KA5. Each is linked with PDCD4 in more than 9 cancer types. Because this analysis shows association rather than direction, both PDCD4-to-partner and partner-to-PDCD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDCD4 versus PDCD4_S457 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD4→partner) and Y-score (partner→PDCD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PDCD4_S457 →	+0.617	+0.728	<.001	<.001	3	10
UCEC	PDCD4_S76 →	+0.931	+1.119	<.001	<.001	3	7
GBM	RPS6KA5 →	+0.575	+0.572	<.001	<.001	3	6
OV	HDLBP_S944 →	-0.565	-0.527	.005	.008	3	5
LUAD	PDCD4_S68 →	+1.159	+0.519	<.001	.008	3	5
OV	PDCD4_S71 →	+1.278	+0.747	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,608 associations by consensus.

PDCD4 vs PDCD4_S457 — HNSC

Explore this scatter interactively →