PDCD2

Across TCGA patient cohorts, PDCD2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,533 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDCD2-associated genes across cancer lineages are TCP1, TBP, and LTV1. Each is linked with PDCD2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PDCD2-to-partner and partner-to-PDCD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDCD2 versus TCP1 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD2→partner) and Y-score (partner→PDCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TCP1 →	+0.631	+0.328	.003	<.001	3	6
GBM	TBP →	+0.438	+0.448	<.001	<.001	3	5
OV	LTV1 →	+0.539	+0.666	.001	<.001	3	5
OV	PSMB1 →	+0.734	+0.787	<.001	<.001	3	5
LSCC	NUP43 →	+0.430	+0.331	<.001	<.001	3	4
OV	PCMT1 →	+0.574	+0.639	.009	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,533 associations by consensus.

PDCD2 vs TCP1 — UCEC

Explore this scatter interactively →