PDCD1LG2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PDCD1LG2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,963 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDCD1LG2-associated genes across cancer lineages are IFFO1, AKNA, and DUSP1. Each is linked with PDCD1LG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDCD1LG2-to-partner and partner-to-PDCD1LG2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD1LG2→partner) and Y-score (partner→PDCD1LG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADIFFO1 →+0.875+0.700.002<.00132
LUADAKNA →+0.994+0.565.001<.00132
GBMDUSP1 →+1.671+0.509<.001.00132
GBMPNPLA7 →+0.689+0.512.008<.00132
LSCCPOLR3B →-0.746-0.603<.001<.00132
GBMADAMTSL4 →+0.851+0.592.004<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,963 associations by consensus.

Exploration