PDCD1LG2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PDCD1LG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,891 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PDCD1LG2-associated GO terms across cancer lineages are Positive regulation of blood coagulation, Urokinase plasminogen activator signaling pathway, and Positive regulation of hemostasis. Each is linked with PDCD1LG2 in more than 14 cancer types. Because this analysis shows association rather than direction, both PDCD1LG2-to-partner and partner-to-PDCD1LG2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD1LG2→partner) and Y-score (partner→PDCD1LG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASPositive regulation of blood coagulation →+0.242+0.920<.001<.001315
BREASTUrokinase plasminogen activator signaling pathway →+1.362+1.040<.001<.001315
PANCREASPositive regulation of hemostasis →+0.242+0.920<.001<.001315
LUNG_NSCLC_LUSCRegulation of smooth muscle cell-matrix adhesion →+1.777+2.008<.001<.001315
BREASTActivation of blood coagulation via clotting cascade →+0.447+1.210<.001<.001315
LIVERCortisol metabolic process →-1.573-2.077.002<.001315
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,891 associations by consensus.

Exploration