PDCD11

Across TCGA cell cohorts, PDCD11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,662 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PDCD11-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase I promoter, Nucleolar large rRNA transcription by RNA polymerase I, and Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with PDCD11 in more than 19 cancer types. Because this analysis shows association rather than direction, both PDCD11-to-partner and partner-to-PDCD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase I promoter grouped by PDCD11-low versus PDCD11-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD11→partner) and Y-score (partner→PDCD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Transcription initiation at RNA polymerase I promoter →	+0.177	+1.017	<.001	.003	3	20
BONE	Nucleolar large rRNA transcription by RNA polymerase I →	+0.112	+0.788	<.001	<.001	3	20
LIVER	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.138	+1.183	.001	.001	3	19
LIVER	rRNA processing →	+0.124	+1.180	.003	.001	3	19
URINARY_TRACT	rRNA metabolic process →	+0.114	+1.015	.001	.002	3	19
BONE	Maturation of SSU-rRNA →	+0.153	+1.121	<.001	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,662 associations by consensus.

Transcription initiation at RNA polymerase I promoter by PDCD11 expression — OESOPHAGUS

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