PDCD11

Across TCGA cell cohorts, PDCD11 mutation is significantly associated with the RNA expression of many other genes, with 1,146 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PDCD11-associated genes across cancer lineages are SAMD8, ZNF804B, and EIF3L. Each is linked with PDCD11 in more than 2 cancer types. Because this analysis shows association rather than direction, both PDCD11-to-partner and partner-to-PDCD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAMD8 grouped by PDCD11-low versus PDCD11-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD11→partner) and Y-score (partner→PDCD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SAMD8 →	+0.597	+3.366	.001	.002	3	3
BLOOD_Lymphoma	ZNF804B →	+0.013	+4.350	<.001	.005	3	2
LARGE_INTESTINE	EIF3L →	+0.512	+3.409	<.001	<.001	3	2
LARGE_INTESTINE	ACBD5 →	+0.793	+2.364	<.001	<.001	3	2
LARGE_INTESTINE	ZNF330 →	+0.453	+3.043	.001	<.001	3	2
LARGE_INTESTINE	TTC19 →	+0.687	+3.459	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,146 associations by consensus.

SAMD8 by PDCD11 expression — BLOOD_Leukemia

Explore this box plot interactively →