PDCD10

Across TCGA pan-cancer cohorts, PDCD10 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PDCD10 data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher PDCD10 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated PDCD10 expression acts as an unfavorable survival marker.

UVM, LUSC, and UCEC are the cancer types where PDCD10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.032	0.762	<.001	30	view →
LUSC	OS	Median	All	0.232	0.777	<.001	24	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PDCD10–UVM (DFS)

Open the UVM breakdown →