PDCD10

Across TCGA cell cohorts, PDCD10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,255 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDCD10-associated GO terms across cancer lineages are Golgi reassembly, Programmed cell death in response to reactive oxygen species, and Hydrogen peroxide-mediated programmed cell death. Each is linked with PDCD10 in more than 15 cancer types. Because this analysis shows association rather than direction, both PDCD10-to-partner and partner-to-PDCD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi reassembly grouped by PDCD10-low versus PDCD10-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD10→partner) and Y-score (partner→PDCD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Golgi reassembly →	+0.143	+1.031	<.001	<.001	3	16
STOMACH	Programmed cell death in response to reactive oxygen species →	+0.174	+0.840	<.001	<.001	3	15
STOMACH	Hydrogen peroxide-mediated programmed cell death →	+0.118	+0.719	<.001	<.001	3	14
STOMACH	Intrinsic apoptotic signaling pathway in response to hydrogen peroxide →	+0.118	+0.719	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Response to arsenite ion →	+0.117	+1.532	.005	<.001	3	13
LUNG_NSCLC_LUSC	Cellular response to arsenite ion →	+0.117	+1.532	.005	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,255 associations by consensus.

Golgi reassembly by PDCD10 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →