PDCD10

Across TCGA cell cohorts, PDCD10 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PDCD10-associated genes across cancer lineages are SLC17A1, COX6A2, and BPIFB6. Each is linked with PDCD10 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDCD10-to-partner and partner-to-PDCD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC17A1 grouped by PDCD10-low versus PDCD10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD10→partner) and Y-score (partner→PDCD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC17A1 →	+0.040	+3.878	.001	.003	3	1
LARGE_INTESTINE	COX6A2 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	BPIFB6 →	+0.016	+4.022	<.001	.006	3	1
LARGE_INTESTINE	WDR87 →	+0.021	+3.453	<.001	.009	3	1
LARGE_INTESTINE	KRT73 →	+0.066	+3.196	.001	.007	3	1
LARGE_INTESTINE	DCANP1 →	+0.011	+3.347	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

SLC17A1 by PDCD10 expression — LARGE_INTESTINE

Explore this box plot interactively →