Across TCGA cell cohorts, PDCD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,289 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDCD1-associated GO terms across cancer lineages are Negative regulation of mRNA processing, Microtubule bundle formation, and Regulation of T cell differentiation. Each is linked with PDCD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PDCD1-to-partner and partner-to-PDCD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD1→partner) and Y-score (partner→PDCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of mRNA processing →	+0.088	+1.129	<.001	.002	3	6
BLOOD_Lymphoma	Microtubule bundle formation →	-0.029	-1.006	.007	.003	3	5
BLOOD_Leukemia	Regulation of T cell differentiation →	+0.058	+0.888	<.001	<.001	3	5
BLOOD_Lymphoma	Cytoplasmic translation →	+0.061	+1.178	<.001	<.001	3	5
BLOOD_Lymphoma	Negative regulation of mRNA splicing, via spliceosome →	+0.090	+1.042	<.001	.006	3	5
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.069	+1.111	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,289 associations by consensus.

Exploration

PDCD1 survival (RNA) · tumor vs normal (RNA) · all PDCD1 data types