PDAP1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PDAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,371 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDAP1-associated genes across cancer lineages are LAMTOR4, ATP5MF, and ARF5. Each is linked with PDAP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PDAP1-to-partner and partner-to-PDAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDAP1 versus LAMTOR4 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDAP1→partner) and Y-score (partner→PDAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLAMTOR4 →+1.267+0.257<.001<.00138
HNSCATP5MF →+0.428+0.308.006<.00129
UCECARF5 →+0.727+0.208<.001<.00138
UCECPOLR2J →+0.869+0.216<.001<.00138
UCECBUD31 →+0.695+0.184<.001<.00138
UCECZNHIT1 →+0.920+0.282<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,371 associations by consensus.

PDAP1 vs LAMTOR4 — UCEC

Per-sample scatter of PDAP1 vs LAMTOR4 in UCEC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration