PDAP1

Across TCGA patient cohorts, PDAP1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDAP1-associated genes across cancer lineages are Endothelial cells, mv Endothelial cells, and pDC. Each is linked with PDAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDAP1-to-partner and partner-to-PDAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by PDAP1-low versus PDAP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDAP1→partner) and Y-score (partner→PDAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.038	-2.279	.046	.036	3	1
UCEC	mv Endothelial cells →	-0.029	-3.321	.014	.010	3	1
UCEC	pDC →	+0.054	+3.008	.026	.019	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Endothelial cells by PDAP1 expression — UCEC

Explore this box plot interactively →